Ranstam Review DataBase (RR.db)

Templates for phenomenon "no difference"

  1. Statistical nonsignificance is not evidence of equivalence. It just indicates uncertainty, and this cannot be used as an argument for "no difference". An equivalence trial or a non-inferiority trial is necessary to show equivalence or non-inferiority.

  2. The results presentation seems to be based on the misconception that observed differences only "exist" if they are statistically significant and that the clinical relevance of differences, existing or not, is irrelevant. I recommend reconsidering this approach to statistical inference. See also Ranstam J. "There was no difference (p = 0.079)". Acta Orthopaedica 23 April 2021.


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